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儿童甲状腺恶性瘤:它位于哪里?
Hasibe Gokce Cinar1, Cigdem Uner1, Ozlem Kadirhan2
1Department of Radiology, Dr. Sami Ulus Training and Research Hospital, Ankara, Turkey.
Archives of endocrinology and metabolism
|May 30, 2023
概括
儿童甲状腺结节的位置可以预测癌症风险. 甲状腺中部的结节显著增加恶性瘤的可能性,这表明位置是一个关键因素.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 关于儿童群体甲状腺结节位置和恶性瘤风险的研究有限.
- 之前在成年人身上进行的研究,对结节的位置和癌症风险产生了不一致的结果.
研究的目的:
- 调查甲状腺结节的位置与儿童恶性瘤风险之间的关联.
- 为了确定结节的位置是否可以作为儿童患者甲状腺癌的预测因素.
主要方法:
- 对103名患有病理诊断的儿科患者 (<18岁) 的97个甲状腺结节进行了回顾性分析.
- 使用甲状腺成像报告和数据系统 (TI-RADS) 算法对结节进行分类.
- 记录结节的位置 (右叶,左叶,峡谷,上极,下极,中极) 并将甲状腺划分为上,中和下部分.
主要成果:
- 在97个结节中,47个是恶性的 (48.5%) 和50个是良性的 (51.5%).
- 在恶性瘤风险和右叶,左叶或峡谷中的结节位置之间没有发现显著的相关性 (P=0.38).
- 恶性结节在中叶 (23%,P=0.002) 的频率显著增加,恶性瘤的风险增加了11.3倍 (OR=11.3,P=0.006).
结论:
- 甲状腺结节的位置是儿科患者恶性瘤的潜在预测因素.
- 甲状腺结节的中叶位置显著提高恶性瘤的风险.
- 将结节位置评估与TI-RADS分类结合起来,可以提高儿童恶性瘤预测的准确性.
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