计划性甲状腺切除术:高血危机中的新标准
Murilo Catafesta das Neves1, Marcello Rosano2, Monique Nakayama Ohe3
1Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Universidade Federal de São Paulo, São Paulo, SP, Brasil, muriloneves@hotmail.com.
Archives of endocrinology and metabolism
|May 30, 2023
概括
甲状腺功能过高引起的高血危机 (HIHC) 是一种严重的疾病,需要及时干预. 手术是最终的治疗方法,特别是对于对初始临床措施反应不佳的患者,以预防并发症.
科学领域:
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 在瘤学瘤学.
背景情况:
- 原发性偏甲状腺症 (PHPT) 可能导致严重的高血症.
- 甲状腺过敏诱发的高热血危机 (HIHC) 是PHPT的一个关键表现.
- 了解HIHC的临床特征和结果对于及时管理至关重要.
研究的目的:
- 阐明甲状腺上升引起的高热血危机 (HIHC) 的临床特征.
- 评估各种治疗策略及其在因PHPT而导致严重高血症的患者的结果.
- 确定HIHC中成功管理和预后的预测因素.
主要方法:
- 对诊断为原发性偏甲状腺症 (PHPT) 的患者历史队列的回顾性分析.
- 根据水平和临床表现,患者被分为三组:HIHC,需要住院治疗的严重高血症和需要选择性治疗的稳定高血症.
- 对每个组的临床特征,治疗干预措施和患者结果进行了评估.
主要成果:
- 七名患者呈现HIHC;初步的临床测量显示,四名患者的疗效有限,需要紧急手术,其中一名患者因并发症死亡.
- 在住院期间,九名患有严重高血症 (2组) 的患者得到了成功的治疗.
- 13名中度高血症患者 (3组) 接受了成功的选择性手术.
结论:
- 甲状腺功能过高引起的高血危机 (HIHC) 是一种危及生命的内分泌紧急情况,需要迅速的临床治疗.
- 手术是HIHC的最终治疗方法,应该考虑对所有受影响的患者进行手术.
- 在HIHC病例中,对初始医疗管理的反应不佳,需要立即考虑手术,以避免疾病的进展和临床衰退.
更多相关视频
07:13Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
14.6K
07:12Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
3.6K
相关概念视频
00:59The Parathyroid Glands
2.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
2.2K
00:51Synthesis and Functions of Calcitonin
2.0K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
2.0K
01:21Skeleton and Calcium Homeostasis
4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K
01:17Hormones and Bone Tissue
2.8K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.8K
01:25Urinary Tract Calculi VI: Surgical Management
11
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
11
01:29Chronic Pancreatitis II: Collaborative Care
117
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
117