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在MiniMedTM 780G高级混合闭环系统与GuardianTM 4传感器早期使用期间的血糖结果
Toni L Cordero1, Zheng Dai1, Arcelia Arrieta2
1Medtronic, Northridge, California, USA.
Diabetes technology & therapeutics
|May 30, 2023
概括
带有GuardianTM 4传感器的MiniMedTM 780G系统在青少年和成年人中证明了安全有效的葡萄糖控制. 这种先进的混合闭环系统改善了血糖指标,显示了糖尿病管理的前景.
科学领域:
- 内分泌学 在内分泌学.
- 生物医学工程 生物医学工程
- 糖尿病 技术 技术
背景情况:
- 之前的研究表明,MiniMedTM先进混合闭环 (AHCL) 系统与GuardianTM传感器3的优势.
- 带有GuardianTM 4传感器 (MM780G+G4S) 的MiniMedTM 780G系统提供无校准的连续血糖监测 (CGM).
研究的目的:
- 评估MM780G+G4S在参与者从以前的系统过渡的早期结果.
- 将这些结果与来自大量用户群的现实数据进行比较.
主要方法:
- 对持续访问研究 (CAS) 参与者和现实世界用户的血糖指标,胰岛素输送和系统使用的描述性分析.
- 从109名儿科和67名成人CAS参与者以及超过36000名现实世界用户收集的数据.
- 分析所需的CGM数据至少需要10天.
主要成果:
- 高时间在先进的混合闭环 (AHCL) 和CGM使用 (>90%) 与最小的系统退出和血糖测量.
- 两个群体中的成年人满足了大多数血糖目标建议.
- 儿科组实现了范围内的时间 (TIR) 和范围以下时间 (TBR) 的目标,通过优化设置,有可能改善葡萄糖变异性和范围以上时间 (TAR).
结论:
- MM780G+G4S系统在早期临床使用中是安全的,用户干预最小.
- 结果与现实世界的数据保持一致,证明了达到推的血糖指数目标.
- 该系统显示出在儿童和成人群体中改善糖尿病管理的巨大潜力.
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