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Updated: Jul 28, 2025

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在患有MLL3/4-COMPASS表观遗传调节器突变的癌症中治疗代谢脆弱性的治疗向

Zibo Zhao1,2, Kaixiang Cao1,2, Jun Watanabe1,3

  • 1Department of Biochemistry and Molecular Genetics.

The Journal of clinical investigation
|May 30, 2023
PubMed
概括

在MLL3/4表观遗传酶中发生的突变会在 purin 合成中产生漏洞. 具有这些突变的癌细胞对药物隆美特雷克索尔敏感,提供了一个新的治疗点.

关键词:
结肠直肠癌是一种癌症.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.遗传学 遗传学 是一个代谢过程中的代谢.

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