使用失去了生命年数重新排名癌症死亡率
Cecilia Radkiewicz1,2, Therese M-L Andersson3, Jesper Lagergren1,4
1Upper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
JNCI cancer spectrum
|May 30, 2023
概括
失去了生命年数 (YLL) 为癌症负担提供了新的视角,揭示了主要固体瘤排名的变化. 这一指标强调了癌症对年轻人群和特定性别的影响.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 癌症负担通常以发病率和死亡率来衡量.
- 这些指标不考虑死亡的年龄,可能低估了某些癌症的社会影响.
- 需要更全面的测量来了解癌症对预期寿命的全部影响.
研究的目的:
- 为了计算瑞典十大最致命的固体瘤的生命损失年数 (YLL).
- 将YLL指标与癌症趋势的传统死亡率数据进行比较.
- 分析十年来主要癌症年龄的性别特异性差异.
主要方法:
- 使用了瑞典国家癌症和死亡原因登记册.
- 肺癌,结肠直肠癌,前列腺癌,胰腺癌,乳腺癌,肝胆癌,尿路癌,中枢神经系统癌,胃癌和黑色素瘤癌的计算年龄.
- 分析了2010年至2019年的YLL趋势,与2019年的死亡率数据进行比较.
主要成果:
- 肺癌和结直肠癌在2019年拥有最高的YLL.
- 胰腺癌在YLL中排名第三,从第四上升,而乳腺癌排名第四,从第五上升.
- 前列腺癌在YLL排名中从第三名下降到第五名.
- 由于肺癌和胰腺癌,妇女总是失去更多的生命年数.
- 结肠直肠癌死亡率的下降仅反映在女性的年龄LL减少.
结论:
- 失去了生命年数 (YLL) 提供了对癌症负担的直观和有价值的衡量标准,补充了传统的死亡率数据.
- YLL强调了癌症对过早死亡率和社会损失的影响.
- 这一指标揭示了癌症影响的重要性别差异,特别是肺癌和胰腺癌.
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