饮食中的黄醇可以恢复老年人的海马体依赖性记忆,饮食质量较差,习惯性黄醇消费较低
Adam M Brickman1,2,3, Lok-Kin Yeung1,2,3, Daniel M Alschuler4
1Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032.
概括
来自可可提取物的食黄醇改善了老年人饮食不良的记忆力. 低醇摄入量可能会导致与年龄相关的记忆力下降,这表明消耗-补充效应.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 在水果和蔬菜中发现的食类黄醇与认知衰老有关.
- 以前的研究表明,黄可能有利于海马体依赖的记忆,受饮食质量的影响.
研究的目的:
- 为了测试饮食中的黄醇是否能改善老年人的记忆力.
- 调查饮食质量是否调节了黄醇对记忆力的干预作用.
主要方法:
- 一项为期3年的随机试验 (COSMOS-Web) 涉及3,562名老年人.
- 使用可可提取物 (每天500毫克黄) 或安慰剂进行干预.
- 通过生物标志物评估习惯性饮食质量和醇摄入量.
主要成果:
- 习惯性醇摄入量和饮食质量与海马体依赖的记忆相关.
- 黄醇干预恢复了参与者基线摄入量或饮食质量较低的记忆力.
- 增加的醇生物标志物水平与记忆力改善相关.
结论:
- 饮食中的黄醇可能会在认知衰老中以耗尽-补充的方式起作用.
- 低醇消费可能会导致与年龄相关的记忆力下降.
- 干预的好处最明显的是在非最佳的黄摄入量和饮食质量的人群.
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