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类固醇受体联合激活剂3是调控性T细胞介导的瘤逃避的关键调节器

Sang Jun Han1,2, Prashi Jain1, Yosef Gilad1

  • 1Department of Molecular Cellular Biology, Baylor College of Medicine, Houston, TX 77030.

Proceedings of the National Academy of Sciences of the United States of America
|May 30, 2023
PubMed
概括

在调节性T细胞 (Tregs) 中删除类固醇受体辅激剂3 (SRC-3) 通过增强抗瘤免疫力,消除乳腺和前列腺瘤. 删除SRC-3的Tregs可以防止瘤复发,而不会引起自身免疫副作用.

关键词:
收养细胞转移的收养细胞转移干扰素-γ-γ 的作用.监管T细胞的监管性T细胞类固醇受体协活性剂3 类固醇受体协活性剂3乳腺癌的同基因小鼠模型.

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