对沃尔巴基亚在越南的登革热控制部署的经济评估
Hugo C Turner1, Duong Le Quyen2, Reynold Dias3
1MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, United Kingdom.
PLoS neglected tropical diseases
|May 30, 2023
概括
引入感染Wolbachia细菌的蚊子提供了一个新的登革热控制策略. 越南的大规模部署具有成本效益,社会经济效益超过干预成本.
科学领域:
- 控制载体传播疾病 控制载体传播疾病
- 公共卫生干预措施 公共卫生干预
- 卫生计划的经济分析.
背景情况:
- 登革热是一个重大的全球公共卫生挑战,由气候变化加剧.
- 使用沃尔巴基亚细菌对抗埃及蚊虫 (Aedes aegypti) 是对登革热的新兴策略.
- 需要对沃尔巴基亚干预措施进行大规模的经济评估.
研究的目的:
- 评估大规模Wolbachia部署对越南登革热的经济影响和成本效益.
- 针对高负担的城市地区进行干预分析.
主要方法:
- 在越南确定了10个优先设置,用于Wolbachia种群替代战略.
- 假设75%的有效性在减少症状登革热病例,持续至少20年.
- 从卫生部门和社会角度进行了成本效益和成本效益分析.
主要成果:
- 从卫生部门的角度来看,沃尔巴基亚干预的成本为每年残疾调整寿命 (DALY) 420 美元.
- 从社会角度来看,经济效益超过了成本,导致负成本效益比率.
- 干预仍然具有成本效益,即使假设10年的收益.
结论:
- 针对性地在越南高负担城市部署Wolbachia是一种具有成本效益的登革热控制战略.
- 这种干预除了直接的健康益处之外,还带来了更广泛的经济效益.
- 沃尔巴基亚释放的持续有效性对于最大化长期经济优势至关重要.
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