患有严重发烧与血小板缺血综合征的患者死亡的危险因素
Kai Yang1, Jun Chen1, Zhiyi Chen1
1Department of Intensive Care Unit, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China.
概括
这项研究确定了年龄,APACHE II评分和血管活性药物作为严重发烧与血栓塞维症综合征 (SFTS) 患者死亡率的关键预测因素. 结合这些因素的新型评分系统改善了SFTS的风险预测.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 严重发烧与血小板缺血综合征 (SFTS) 是一种具有显著死亡率的新兴传染病.
- 准确的风险分层对于及时有效的患者管理至关重要.
研究的目的:
- 建立一个可克斯回归模型,用于预测SFTS患者的死亡风险因素.
- 开发和验证SFTS死亡率的预测评分系统.
主要方法:
- 在2016年6月至2020年10月期间,对109名SFTS患者进行了回顾性分析.
- 单变量和二进制物流回归分析以确定风险因素.
- 接收器操作特征 (ROC) 曲线分析用于预测模型评估.
主要成果:
- 确定了SFTS死亡率的独立风险因素:年龄,APACHE II评分和血管活性药物.
- 开发了一个联合预测方程:联合预测因子 = 年龄 + 3.162 × APACHE II 评分 + 22.306 × 血管活性药物.
- 与单个因素相比,综合预测因素显示出更高的预测价值.
结论:
- 年龄,APACHE II评分和血管活性药物是SFTS死亡率的重要独立风险因素.
- 开发的SFTS评分系统有效地整合了这些因素,以改善临床风险评估.
- 这种评分系统有助于确定风险因素的可行临床应用.
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