术后免疫营养支持对接受肺癌手术的患者营养和炎症状况的影响:一项前性随机对照研究
Gokce Gunsel-Yildirim1,2, Kenan Can Ceylan3, Derya Dikmen4
1Nutrition and Diet Department, Republic of Turkey Ministry of Health İzmir Provincial Health Directorate Health Sciences University Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, İzmir, Turkey.
概括
术后免疫营养显著改善了肺癌手术患者的营养状况和身体表现. 早期支持对于在肺癌手术 (LCS) 后获得更好的结果至关重要.
科学领域:
- 在瘤学瘤学.
- 手术营养是指手术营养.
- 临床试验 临床试验
背景情况:
- 肺癌手术 (LCS) 对患者的营养状况产生负面影响.
- 手术前营养状况是手术结果的关键因素.
研究的目的:
- 调查术前免疫营养支持对LCS患者营养和炎症状况的影响.
- 为了评估免疫营养对体力活动和整体健康的后术影响.
主要方法:
- 一项前性随机对照试验,涉及70名LCS患者.
- 治疗组接受了手术前和后的口服免疫营养.
- 用患者生成的主观全球评估 (PG-SGA),预后营养指数 (PNI) 和系统性炎症指数 (SII) 评估营养状况.
主要成果:
- 与对照组相比,治疗组的术后营养状况 (PG-SGA,p=0.009) 和身体表现 (ECOG-PS,p=0.001) 显著改善.
- 两组都经历了手术后营养状况和身体表现的下降,但治疗组的下降程度不那么严重.
- 术后PNI水平下降,SII水平增加,表明炎症变化.
结论:
- 术后免疫营养支持对接受LCS的患者是有益的.
- 在手术前启动免疫营养可以促进恢复并改善结果.
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