非小细胞肺癌的治疗方法:临床实践指南的系统质量评估
Marcela Cortés-Jofré1,2, Meisser Madera3, Lesbia Tirado-Amador4
1Doctoral Program in Research Methodology and Public Health, Universitat Autònoma de Barcelona, Barcelona, Spain.
概括
这项研究评估了非小细胞肺癌 (NSCLC) 治疗临床实践指南 (CPG) 的质量. 虽然整体上是温和的,但CPG需要在开发和实施方面进行改进,以获得更好的患者护理.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 基于证据的医学基于证据的医学.
背景情况:
- 非小细胞肺癌 (NSCLC) 需要标准化的治疗方法.
- 临床实践指南 (CPG) 旨在基于当前证据标准化护理.
- 评估NSCLCCPG的质量对于确保可靠的治疗建议至关重要.
研究的目的:
- 系统地评估现有的非小细胞肺癌 (NSCLC) 治疗临床实践指南 (CPG) 的方法质量.
- 确定NSCLC CPGs开发和报告中的特定优势和弱点.
主要方法:
- 在数据库 (MEDLINE) 和相关组织网站上进行了全面的文献搜索.
- 确定和评估了22种用于NSCLC治疗的CPG.
- 研究和评估指南评估II (AGREE II) 工具由三个评估人员独立应用,以确定方法质量.
主要成果:
- 在AGREE II领域的方法质量得分各不相同,在范围和目的 (90.7%) 和编辑独立 (91.7%) 方面得分很高.
- 在适用性 (46.5%) 和利益相关者参与度 (76.9%) 中观察到较低的分数,这表明实施的潜在障碍.
- 超过一半的CPG (54.5%) 建议进行修改,这表明有改进的余地.
结论:
- NSCLC CPG 的整体方法质量是中等的.
- 存在显著的机会来加强这些指导方针的制定和实施.
- 提高指导方针的质量可以导致非小细胞肺癌的更一致和更有效的管理.
更多相关视频
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
50.1K
06:03Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
Published on: May 23, 2015
22.4K
相关概念视频
Standards of Care II
692
Nurses bear specific legal responsibilities under several federal statutes, including:
692
Cancer Therapies
7.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.8K
Standards of Care I
731
Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:
731
Cancer Survival Analysis
402
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
402
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K
Clinical Trials: Overview
3.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.1K
