在低负担和中等负担国家,结核性脑膜炎的婴儿中,干扰素-γ释放试验和曼托克斯反应
Yan-Hua Yang1, Jie Hou2, Yu He3
1The Immunetech Institute of Guilin, Guilin, 541004, China.
BMC infectious diseases
|May 30, 2023
概括
曼托克斯测试显示,在低结核病负担的国家,婴儿结核性脑膜炎 (TBM) 诊断的表现不佳. 干扰素-γ释放试验 (IGRAs) 显示出对诊断婴儿TBM的中度敏感性.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 婴儿结核性脑膜炎 (TBM) 的诊断仍然具有挑战性,特别是在低和中等结核病 (TB) 负担的环境中.
- 干扰素γ释放试验 (IGRA) 和婴儿TBM的曼托克斯试验的诊断效用需要进一步评估.
结论:
- 曼托克斯试验在低或中等结核病负担的国家的婴儿中诊断TBM的灵敏度较差.
- 干扰素-γ释放试验 (IGRA) 具有中度灵敏度,表明它有可能作为婴儿TBM的诊断工具.
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