乳制品和植物性蛋白质饮料:体外消化行为和对肠道屏障生物标志物的影响
Elena Arranz1, Annalisa Segat2, Gemma Velayos2
1Teagasc Food Research Centre, Moorepark, Fermoy, Co Cork P61 C996, Ireland.
Food research international (Ottawa, Ont.)
|May 31, 2023
概括
饮料中的植物蛋白与乳制品蛋白相比,显示出类似的消化和肠道健康影响. 这支持在营养饮料中使用植物性替代品,满足不断增长的消费者需求.
科学领域:
- 食品科学 食品科学 食品科学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 越来越多的消费者对蛋白质丰富食品和植物性替代品的需求.
- 营养饮料是植物蛋白替代的一个关键领域.
- 了解蛋白质消化和肠道健康影响对于产品开发至关重要.
研究的目的:
- 将乳制品与植物性粉末饮料的蛋白质消化和肠道屏障健康情况进行比较.
- 评估模拟胃肠道消化对饮料成分的影响.
- 评估消化饮料对肠道细胞模型的影响.
主要方法:
- 模拟乳制品和植物性饮料的体外胃肠道消化.
- 对体大小和消化后释放的自由氨基酸的分析.
- 在实验室中使用Caco-2/HT-29/MTX共同培养物进行肠道透性评估.
- 测量紧结蛋白,粘液蛋白和IL-8 mRNA的表达.
主要成果:
- 所有饮料在消化后都增加了自由氨基酸的释放;大多数是<0.8kDa.
- 预化成分在消化后没有显示增加的水解.
- 消化的植物饮料显示出与乳制品饮料相似的肠道屏障生物标志物反应 (紧结,粘液,IL-8 mRNA).
- 肠道屏障阻抗保持不变,但炎症标志物增加.
结论:
- 植物性蛋白质饮料的蛋白质消化概况与基于乳制品的蛋白质饮料相似.
- 对消化的植物蛋白的肠道屏障反应类似于乳制品蛋白.
- 这些发现支持在粉末饮料配方中用植物蛋白替代乳制品蛋白质的可行性.
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