住院COVID-19患者的他类药物:随机对照试验的系统审查和元分析
Yajuan Ren1, Guizuo Wang1, Dong Han1
1Department of Respiratory and Critical Care Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Journal of medical virology
|May 31, 2023
概括
这次审查发现,他类药物没有显著降低COVID-19住院患者的死亡率或住院时间. 根据目前的证据,不建议在这些患者中常规使用他类药物.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 类药物是常见的降脂药物,具有潜在的抗炎和免疫调节作用.
- 对于2019年冠状病毒病 (COVID-19) 住院患者的结果,他类药物的影响仍然不清楚.
结论:
- 对于降低住院COVID-19患者的死亡率,ICU入院,机械通风或住院时间,他类药物没有任何好处.
- 这些发现表明,他类药物可能不应该定期给住院的COVID-19患者服用.
- 可能需要进一步的研究来探索潜在的子组效应或特定的迹象,如果有的话.
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