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Updated: Jul 28, 2025

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不同的过度活跃的RAS/MAPK等位基因汇聚在共同的GABAergic内部神经元核心程序上

Sara J Knowles1, April M Stafford2, Tariq Zaman2

  • 1School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.

Development (Cambridge, England)
|May 31, 2023
PubMed
概括

在发育中的脑细胞中RAS/MAPK通路过度激活会改变GABAergic内部神经元程序. 这项研究揭示了突变如何影响神经发育,并可能为相关认知障碍的治疗提供信息.

关键词:
在 Nf1 的情况下.bRafaf 的意思是皮层内部神经元的内部神经元这就是MAPKK的意思.拉索病症是一种RAS病症.索马托斯塔丁是一种体质的药物.

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