在非正式的工作中是否存在与SARS-CoV-2感染相关的化学物质暴露?
Fernanda Junqueira Salles1, Isabelle Nogueira Leroux1, Alda Neis Miranda de Araujo2
1Universidade de São Paulo. Faculdade de Saúde Pública. Departamento de Saúde Ambiental. São Paulo, SP, Brasil.
Revista de saude publica
|May 31, 2023
概括
非正式的家庭工人,如接工人,表现出越来越多的COVID-19症状的趋势,但更好的社会距离遵守可能会保护他们. 出租车的使用是发展症状的重要风险因素.
科学领域:
- 职业健康 职业健康 职业健康
- 环境健康 环境健康
- 传染病流行病学 传染病流行病学
背景情况:
- 随着COVID-19的爆发,人们意识到了解感染和症状发展的风险因素的重要性.
- 暴露在潜在有毒元素 (PTEs) 的工人可能具有独特的健康弱点.
- 职业化学物质暴露对SARS-CoV-2感染风险的影响尚未得到充分证实.
研究的目的:
- 为了比较非正式家庭工人 (接工) 和对照组之间的COVID-19症状发生率.
- 评估COVID-19病例,血液元素度和风险因素之间的关联.
- 调查社会距离遵守在接工和控制中的作用.
主要方法:
- 一组26名暴露于化学物质的接工人和25名对照人员在五个月内完成了症状和社交距离调查问卷.
- 在大流行之前,用ICP-MS分析了血液样本以检测PTE度 (As, Mn, Ni, Cd, Hg, Sb, Sn, Cu, Zn, Pb).
- COVID-19 血清学测试是在次样本后跟踪后进行的.
主要成果:
- 暴露于化学物质的工人血中的 (Pb) 和 (Cd) 含量显著增加.
- 对照组对社交距离措施的遵守程度较低.
- 接工人对COVID-19症状的趋势不显著 (74%更高的机会),随着更好的社交距离减少了20%;出租车使用是一个显著的风险因素.
结论:
- 对照组中较低的社会距离遵守显著影响了COVID-19的发展.
- 该研究发现PTE暴露与SARS-CoV-2感染或严重程度之间没有显著的联系.
- 在家工作和更大的社会距离遵守可能已经保护了暴露在化学物质中的接工人免受COVID-19的伤害.
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