研究甘油三指数与冠状动脉慢流之间的关系:一项回顾性病例对照研究
Mustafa Kaplangoray1, Kenan Toprak2, Fuat Başanalan1
1Departamento de Cardiologia - University of Health Sciences Mehmet Akif İnan Research and Training Hospital , Sanlıurfa - Turquia.
Arquivos brasileiros de cardiologia
|May 31, 2023
概括
甘油三糖 (TyG) 指数与冠状动脉慢流 (CSF) 密切相关,这是一种影响心脏动脉血液流动的疾病. 9.28或更高的TyG指数可以预测CSF.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 血管生理学 血管生理学
背景情况:
- 冠状动脉缓慢流 (CSF) 的特点是延迟远部血管模糊,没有显著的心表狭窄.
- 在CSF的基本机制仍然不完全理解.
研究的目的:
- 调查甘油三糖指数 (TyG) 和冠状动脉慢流 (CSF) 之间的关联.
主要方法:
- 该研究包括118名CSF患者和105名正常冠状动脉流量 (NCF) 对照.
- 冠状动脉流量率通过肌心梗塞 (TIMI) 中的血栓分析 (Thrombolysis in Myocardial Infarction,TIMI) 框架计数 (TFC) 来评估.
- TyG指数的计算形式是: log ((禁食甘油三醇 × 禁食葡萄糖 / 2).
主要成果:
- 与NCF相比,CSF患者的TyG指数,BMI,LDL,NLR和吸烟比率较高,HDL较低.
- 脑脊液与TyG指数 (r=0.57,p<0.001),BMI,NLR和HDL有很强的相关性.
- 多变量分析确定了TyG指数,BMI,NLR和男性性别作为CSF的独立预测因素.
- 一个TyG指数切线≥9.28预测的CSF具有78%的灵敏度和78.1%的特异性 (AUC:0.868).
结论:
- 在甘油三糖指数 (TyG) 和冠状动脉慢流 (CSF) 之间存在显著而强烈的关系.
- TyG指数作为冠状动脉慢流的潜在预测标记.
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