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Updated: Jul 28, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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在T细胞中,PTPN22通过14-3-3τ激活PI3K通路

Bin Bai1, Tao Wang1, Xiaonan Zhang1

  • 1Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.

The FEBS journal
|May 31, 2023
PubMed
概括

蛋白氨酸酸酶PTPN22通过调节14-3-3τ和PI3K信号来调节T细胞激活. 这种机制抑制了促炎因素,为自身免疫性疾病预防提供了洞察力.

关键词:
14-3-3ττ 这是一个很好的例子.在PI3K中,PI3K是指PI3K.在PTPN2222中使用.脱酸酸盐的使用方法互动互动互动互动互动互动

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