移民中的结核病:流行病学,耐药性和结果在意大利米兰,意大利
Niccolò Riccardi1,2, Roberta Maria Antonello1, Maurizio Ferrarese1,3
1StopTB Italia Onlus, Milan, Italy.
Infectious diseases (London, England)
|May 31, 2023
概括
人类迁移影响结核病 (TB) 流行病学. 这项研究发现,移民的抗药性结核病发病率更高,而意大利人的死亡率和肺外结核病发病率更高. 对于这两个群体都需要量身定制的方法.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 全球的人类迁移和地缘政治变化正在改变结核病 (TB) 流行病学.
- 低结核病负担的国家面临着由于来自高结核病负担地区的移民而增加的结核病病例.
研究的目的:
- 为了比较流行病学,药物耐药性模式和在意大利本土人和移民之间活跃结核病的治疗结果.
- 在结核病控制方面为各种人群量身定制的公共卫生战略提供信息.
主要方法:
- 一项观察性,回顾性,单中心研究在意大利北部进行.
- 分析了10,555名活跃结核病患者 (1990-2019) 的数据,比较了4,614名意大利人和5,941名移民.
- 医疗记录被用来收集关于人口统计,耐药性和结果的数据.
主要成果:
- 移徙者表现出更高的抗利胺 (RR) 或多抗药 (MDR) 结核病率,以及对随访的损失增加.
- 意大利患者的死亡率更高,肺外结核病例比例更高.
- 两组之间观察到显著的流行病学和临床差异.
结论:
- 这项研究代表了意大利最大的活跃结核病患者队列之一.
- 结核病耐药性和结核病结果的不同模式需要针对本地和移民人口量身定制的管理策略.
- 解决结核病需要具体的方法,考虑到不同的人口群体面临的独特挑战.
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