根据分娩方式分类出血乱和产后出血:一项回顾性队列研究
Bonnie Niu1, Lisa Duffett2, Darine El-Chaâr3
1Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Research and practice in thrombosis and haemostasis
|May 31, 2023
概括
患有出血障碍的孕妇面临高分娩后出血 (PPH) 风险. 这项研究发现,阴道分娩和剖腹产之间的PPH率没有显著差异,这凸显了需要进行更大规模的调查的需要.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 患有出血障碍的孕妇有增加周周出血并发症的风险.
- 对于这些患者来说,最佳的分娩方式仍然是争论的主题,导致临床不确定性.
研究的目的:
- 分析孕妇的结果,特别是产后出血 (PPH),与患有出血障碍的孕妇的分娩方式有关.
- 调查分娩方式与新生儿出血并发症之间的潜在关联.
主要方法:
- 在一个单一中心从2010-2021年回顾性数据收集.
- 在56名患有出血障碍的个体中,包括82例怀孕.
- 使用描述性统计数据,费舍尔精确测试和赔率比率进行统计分析.
主要成果:
- 最常见的出血障碍是血友病A和·维勒布兰德病 (每一个为30%).
- 总体初级PPH率为7.3%,二级PPH率为17.4%.
- 在阴道和剖腹产之间没有观察到PPH率的统计学上显著差异 (或0.7对于初级PPH,或2.6对于二级PPH).
结论:
- 产后出血仍然是患有出血障碍的孕妇的一个重要并发症.
- 目前的研究没有发现传递方式和PPH率之间存在显著的关联.
- 一个小样本大小有限的统计能力,强调了需要更大的,多中心的研究.
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