在状细胞疾病中自由组织转移:病例报告和系统审查
Anne Huang1, Ronak A Patel1, Lawrence J Gottlieb1
1Section of Plastic and Reconstructive Surgery, University of Chicago Medicine and Biological Sciences, Chicago, Illinois.
Archives of plastic surgery
|May 31, 2023
概括
自由组织转移对于状细胞病 (SCD) 患者来说是一个可行的选择,尽管有传统的担忧. 这项研究强调了SCD患者成功的片重建,并得到了文献审查的支持.
科学领域:
- 重建性微手术是重建性的微手术.
- 血液学 血液学 血液学
- 血管外科 血管外科
背景情况:
- 状细胞病 (SCD) 已被认为是自由组织转移的禁忌,因为存在血栓形成和片衰竭的风险.
- 在SCD患者中,红细胞形可能会损害微血管循环,对重建程序构成挑战.
研究的目的:
- 报告在患有状细胞疾病的患者中成功进行自由组织转移的病例.
- 系统地审查有关SCD患者自由组织转移结果的现有文献.
主要方法:
- 一个SCD患者进行自由组织移植的单个患者的回顾性图表审查.
- 一个系统的文献审查,遵循PRISMA指南,搜索PubMed,Ovid/Medline和Scopus的"免费组织转移"",免费"或"微手术"和"状细胞".
主要成果:
- 在一个29岁的患有SCD的男性身上,成功地用一个自由的前侧大腿关闭了伤口.
- 文献审查在7篇文章中发现了13例病例,SCD患者的完全自由成功率为77% (10/13).
- 关键的术后治疗包括红细胞输血,补水,正常热量,止痛和抗凝药.
结论:
- 在状细胞病患者中,可以安全且成功地进行自由组织转移.
- 对于接受自由组织移植的SCD患者,最佳的术后管理策略需要除病例报告之外进行进一步的调查.
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