预防和控制对抗抗卡巴胺耐药 Enterobacteriaceae 的感染策略 - 一个系统的审查
Catarina Santos-Marques1,2,3, Helena Ferreira2,3, Sónia Gonçalves Pereira1
1Center for Innovative Care and Health Technology - ciTechCare, Polytechnic of Leiria, Portugal.
Journal of infection prevention
|May 31, 2023
概括
有效的感染预防和控制策略对于对抗抗卡巴耐药肠道细菌 (CRE) 传播至关重要. 需要在重症监护室以外进行进一步的研究,以解决实施缺陷.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 微生物学 微生物学
背景情况:
- 抗微生物耐药性,特别是耐卡巴胺的肠杆菌 (CRE),是全球日益严重的健康威胁.
- 感染预防和控制 (IPC) 策略对于管理CRE的全球传播至关重要.
研究的目的:
- 系统地审查和分析IPC策略对控制普遍CRE传播的影响现有证据.
- 为了确定最有效和高效的IPC措施,对抗抗卡巴胺耐药的*Escherichia coli*和*Klebsiella肺炎*.
主要方法:
- 在PubMed,Scopus和Web of Science中对2017年1月至2020年6月期间发表的文章进行了系统的文献搜索.
- 纳入和排除标准应用于11635个已识别的出版物,最终选择了30项相关研究.
主要成果:
- 大多数选择的研究 (24/30) 专注于疫情情况,其中26例发生在急症监护机构,其中17例发生在重症监护病房.
- 通常实施的IPC措施包括监测培养 (29项研究),患者隔离或队列 (23项研究),以及遵守标准和接触预防措施.
结论:
- 对控制CRE传播而言,IPC策略至关重要,这凸显了超越疫情和ICU设置的研究需求.
- 增加投资,全面培训和教育对于所有医疗保健部门有效实施IPC至关重要.
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