在结性脊柱炎中勃起功能障碍:系统性审查和元分析
Yuyang Zhang1,2,3, Xu Wu1,2,3, Wei Zhang1,2,3
1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230031, China.
Sexual medicine
|May 31, 2023
概括
勃起功能障碍 (ED) 影响44%的男性患有结性脊柱炎 (AS). 这项研究证实AS是ED的重要风险因素,突出了AS患者的关键健康问题.
科学领域:
- 类风湿病学 类风湿病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 在结性脊椎炎 (AS) 患者中,勃起功能障碍 (ED) 患病率很少被报告.
- 现有数据通常涉及小样本大小,需要全面分析.
研究的目的:
- 确定在被诊断为AS的男性中ED的流行率.
- 调查AS是否独立地成为ED发展的风险因素.
主要方法:
- 在多个数据库 (PubMed,科学网等) 进行系统的文献搜索. 到2022年10月为止.
- 使用已建立的工具 (纽卡斯尔-太华尺度) 进行包含研究的质量评估.
- 使用相对风险 (RR) 和标准平均差异 (SMD) 评估AS-ED关联的元分析,与子组和灵敏度分析.
主要成果:
- 在AS患者中,ED的综合患病率为44% (95%CI,25%63%).
- 患有AS的男性呈现出明显更高的ED风险 (RR,2.04;95% CI,1.283.25).
- 阿斯患者报告说,国际勃起功能指数 (IIEF) 得分明显较低,特别是在勃起功能领域 (SMD, -0.60;95% CI, -0.80-0.41).
结论:
- 结性脊柱炎与高频率的勃起功能障碍有关.
- AS被确定为一个重要的风险因素,有助于ED在受影响的男性.
- 这一元分析强调了在AS患者护理中管理ED的必要性.
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