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Updated: Jun 13, 2026

Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase
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在患有急性淋巴细胞白血病的儿童中,评估FTO多态性在与6-默卡普图氨酸相关的不耐受性中

Minu Singh1, Divya Bhaskar1, Prateek Bhatia1

  • 1Haematology-Oncology Unit, Department of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Cancer chemotherapy and pharmacology
|May 31, 2023
PubMed
概括

在患有急性淋巴细胞白血病 (ALL) 的儿童中,FTO基因 (FTO-rs16952570) 的遗传变异与提奥普林诱导的骨髓抑制或肝毒性无关. 这一发现表明,FTO-rs16952570在这个患者群体中不是 thiopurine 毒性的预测生物标志物.

关键词:
所有的,所有的,所有的.化疗 化疗是一种化学疗法.IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD IBD维护阶段维护阶段提奥普林是一种类型的氨基酸.

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