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不同程度的腺体缩对儿科上呼吸道空气动力学的影响:一项计算流体动力学研究

Zhenzhen Hu¹, Jingliang Dong^2,3,4, Miao Lou¹

¹Department of Otolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi, China.

Biomechanics and modeling in mechanobiology

|May 31, 2023

概括

腺体缩 (AH) 显著影响儿科上呼吸道 (UA) 空气动力学. 较大的腺会增加空气流速,压力下降和壁压力,影响呼吸道通透度.

科学领域:

儿科耳鼻喉科儿科耳鼻喉科
生物医学工程生物医学工程
计算流体动力学的流体动力学.

背景情况:

腺体缩 (AH) 是儿童常见的疾病.
准确的诊断和了解AH对上呼吸道 (UA) 的影响对于及时干预至关重要.
量化与不同程度的AH相关的空气动力学变化是必不可少的.

研究的目的:

量化分析儿科上呼吸道的空气动力学特征,不同程度的腺体缩.
为了将腺体大小与与腺体-鼻 (AN) 比率表示的腺体大小,与空气流速,压力下降 (△P) 和墙壁剪切应力 (WSS) 相关联.

主要方法:

基于CT扫描的儿科UA模型的虚拟手术重建,具有不同的AN比率 (0.9,0.8,0.7,0.6) 和对照 (0.5) 基于CT扫描.
计算流体动力学 (CFD) 分析以评估峰值速度,△P和最大WSS.

主要成果:

由于流量分离和逆流,在鼻腔和口腔中形成旋.
对于AN比率≥0.7,与鼻区域相比,鼻和鼻区域的气流速度显著增加.
在鼻和鼻中观察到高的△P和最大WSS,AH的严重程度增加.

结论:

腺体大小是儿科上呼吸道通透性的关键决定因素.
显著的空气动力学变化发生在UA中,中度至重度的腺体缩.
这些发现支持改善AH的诊断准确性和及时管理以预防并发症.

关键词:

一个比率AN比率.腺体缩过度增大腺体缩过多空气动力学航空动力学在 CFD 交易中,我们可以看到 CFD.虚拟手术虚拟手术是一种虚拟的手术.

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