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在有或没有精神疾病的成年人中,戒烟以及焦虑和抑郁症的变化
Angela Difeng Wu1, Min Gao1, Paul Aveyard1
1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
JAMA network open
|May 31, 2023
概括
戒烟可以改善心理健康,减少焦虑和抑郁症状. 这一发现为个人和临床医生提供了保证,他们担心戒烟对心理健康的潜在负面影响.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 许多人希望戒烟,但仍然担心戒烟后心理健康可能恶化.
- 临床医生和吸烟者都经常对戒烟对心理健康的后果表示担忧.
研究的目的:
- 通过使用三个强大的分析方法,评估戒烟对心理健康的影响.
- 提供基于证据的见解,了解戒烟与精神健康之间的关系.
主要方法:
- 来自一项大型随机临床试验 (评估全球戒烟研究中的不良事件) 的数据的二次分析,涉及美国参与者.
- 使用多变量托比特回归,倾向得分调整和仪器变量回归来分析焦虑和抑郁得分的变化 (医院焦虑和抑郁量表).
- 敏感性分析包括对缺失数据的归算,重点关注患有和没有精神疾病的参与者.
主要成果:
- 与继续吸烟相比,戒烟与焦虑和抑郁分数的统计学显著下降有关.
- 根据倾向评分调整的模型证实,戒烟导致焦虑 (β = -0.32) 和抑郁 (β = -0.42) 评分降低.
- 观察性分析表明,持续戒烟会改善心理健康结果,特别是在有精神疾病史的人群中.
结论:
- 持续戒烟与改善心理健康结果有关,这与常见的担忧相反.
- 这些发现表明,戒烟不太可能使心理健康恶化,实际上可能会改善心理健康.
- 这些结果可以使吸烟者和医疗保健提供者对戒烟对心理健康的积极影响感到放心.
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