患有淋巴瘤的美国军事服务人员的生存率
Gilbert Ancira1, Joshua Romain2, Kevin Pham3
1Department of Hematology/Oncology, San Antonio Uniformed Service Health Consortium, San Antonio, TX 78234, USA.
Military medicine
|May 31, 2023
概括
与平民相比,患有淋巴瘤的现役服役人员 (ADSM) 的生存率高于平民. 这项研究没有发现基于种族或性别的ADSM存活率有显著差异,这表明军事准备的良好结果.
科学领域:
- 在瘤学瘤学.
- 军事医学 军事医学
- 流行病学 流行病学
背景情况:
- 癌症是现役服役人员 (ADSM) 死亡的主要原因.
- 淋巴瘤是ADSM中最常见的血液性恶性瘤,使其成为生存研究的重点.
- 了解ADSM的癌症存活率对于军事准备和医疗保健政策至关重要.
研究的目的:
- 为了比较被诊断为淋巴瘤的ADSM与匹配的平民人口的整体存活率 (OS).
- 研究基于种族,性别或等级的ADSM患者之间淋巴瘤存活率的潜在差异.
- 评估癌症存活率对军事准备的影响.
主要方法:
- 对国防部瘤登记和监视,流行病学和最终结果 (SEER) 数据库的回顾性分析.
- 包括在1997年至2017年期间被诊断患有霍奇金淋巴瘤 (HL),扩散性大B细胞淋巴瘤 (DLBCL) 和惰性淋巴瘤的ADSM.
- 根据年龄,性别,种族,阶段和诊断年份对平民比较患者的匹配 (比率为 4:1).
主要成果:
- 患有HL,DLBCL和惰性淋巴瘤的ADSM与匹配的平民相比,显示出明显优异的OS.
- 在ADSM中死亡风险的降低为35% (HL),49% (DLBCL) 和48% (惰性淋巴瘤).
- 基于种族,性别或等级的ADSM之间没有观察到生存差异,与平民差异形成鲜明对比.
结论:
- 被诊断为淋巴瘤的ADSM显示出比平民同行更好的生存结果.
- 在ADSM生存中没有种族或性别差异是军事准备的积极发现.
- 建议对ADSM患者的癌症死亡率进行进一步研究,以提高患者的长期治疗结果.
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