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Updated: Jul 28, 2025

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells
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Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells

Published on: March 3, 2015

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对NHEJ机器的PAXX绑定解释了XLF的功能冗余

Murielle Seif-El-Dahan1, Antonia Kefala-Stavridi2, Philippe Frit3

  • 1Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette cedex, France.

Science advances
|May 31, 2023
PubMed
概括

辅助蛋白PAXX在通过非同类末端连接修复DNA双链断裂方面发挥着关键作用. PAXX和XLF一起工作,通过桥接蛋白质二次体来增强DNA修复.

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