复合维生素对接受美沙维持治疗的患者焦虑和抑郁的作用:双盲随机对照试验
Negar Lagzi1, Amin Bateni1, Rasoul Goli2
1Department of Community Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
International journal of psychiatry in medicine
|May 31, 2023
概括
多种维生素补充剂在接受美沙维持治疗 (MMT) 的患者中改善了抑郁症. 然而,复合维生素在这个研究群体中没有显著影响焦虑水平.
科学领域:
- 临床营养学 临床营养学
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
背景情况:
- 阿片类药物成和美沙维持治疗 (MMT) 与严重的心理痛苦有关,包括焦虑和抑郁.
- 营养缺乏会加剧情绪障碍,而多维生素可以提供支持作用.
研究的目的:
- 调查多维生素补充剂在缓解MMT患者焦虑和抑郁症状方面的有效性.
- 评估综合复合维生素配方对脆弱患者群体情绪障碍的影响.
主要方法:
- 一项为期12周的双盲随机对照试验与70名18岁以上的男性MMT患者进行.
- 参与者每天接受多种维生素 (包括维生素E,B组合,C,生物素,叶酸和) 或安慰剂.
- 焦虑和抑郁的水平被评估使用标准化问卷干预前和后.
主要成果:
- 综合维生素和安慰剂组之间没有观察到焦虑得分的显著差异.
- 与安慰剂组相比,在接受多维生素补充剂的组中发现了抑郁症得分的统计学显著降低.
结论:
- 多维生素补充剂在接受MMT的患者中对抑郁症状产生有益影响.
- 虽然不影响焦虑,但复合维生素是一种潜在的辅助疗法,可以改善这种患者队列中的情绪.
相关概念视频
01:23Antidepressant Drugs: MAOIs and Other Agents
285
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
285
01:28Drug Therapy
74
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
74
01:25Antidepressant Drugs: Overview
614
Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
614
01:54The Placebo Effect
6.2K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.2K
01:30Stress and Mental Health
188
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
188
01:18Depression: Overview
294
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
294