微生物群和精液质量:系统审查
Isadora de Almeida Gomes1, Paula Bruno Monteiro2, Gabriel Acácio de Moura3
1Graduating in biomedicine at the Christus University Center - UNICHRISTUS, Fortaleza, CE, Brazil.
JBRA assisted reproduction
|May 31, 2023
概括
人类微生物群对健康有影响. 男性的不孕症可能与肠道细菌失衡有关,较低的乳酸菌和较高的Prevotella与精液质量差有关.
科学领域:
- 微生物学 微生物学
- 生殖健康 生殖健康
- 人类微生物组 人类微生物组
背景情况:
- 人类微生物群,包括居民微生物,显著影响宿主健康和疾病.
- 微生物群失生症与各种病理过程有关,包括男性不孕症.
- 了解肠-精液轴对于生殖健康至关重要.
研究的目的:
- 系统地审查现有的文献,并确定人类微生物群与男性精液质量之间的相关性.
- 调查与正常与改变的精液参数相关的特定微生物物种.
主要方法:
- 2012年至2022年间发表的7项研究的系统审查.
- 在PubMed,Medline和Cochrane图书馆数据库中进行文献搜索.
- 研究仅限于用英语发表的研究.
主要成果:
- 具有正常精液参数的男性表现出更高的乳酸菌种的流行率.
- 患有精液变化的患者表现出更高的Prevotella物种的流行率.
- 有证据表明,与不孕症相关的微生物组成发生了变化.
结论:
- 人类微生物群的组成明显与精液质量相关.
- 在不育的男性中观察到乳酸菌的减少和其他细菌物种的增加,如Prevotella.
- 对微生物群调节的进一步研究可能为男性不孕症提供新的治疗策略.
相关概念视频
Sperm Structure and Semen Composition
3.1K
During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
3.1K
Infertility in Males
299
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
299


