成年人患有大动脉缩的不律性和血栓栓结局
John Shadarevian1, Kai Zhu1, Joanne M Kwan1
1Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
International journal of cardiology
|May 31, 2023
概括
患有大动脉缩 (CoA) 的成年人比普通人群患心房律乱 (AA) 的几率更高. 随着年龄的增长和心脏内干预措施与这些患者的AA有关.
科学领域:
- 心脏病学 心脏病学
- 成人的先天性心脏病 (ACHD)
- 血管医学 血管医学
背景情况:
- 患有先天性心脏病 (ACHD) 的成年人经常经历心房律乱 (AA) 和血栓栓塞事件.
- 有限的AA和长期结果的数据在ACHD患者与大动脉缩 (CoA) 是有限的.
研究的目的:
- 为了确定患有CoA的成年人中AA的患病率.
- 为了确定患有CoA的成年人中AA和血栓栓塞并发症的危险因素.
主要方法:
- 在第三级 ACHD 护理中心进行了回顾性队列研究.
- 包括连续COA患者>18岁,随访时间>1年.
- 随访了270名CoA患者,平均为7.2年.
主要成果:
- 13%的CoA患者发展了AA;3.8%经历了血栓栓塞栓性脑血管事件.
- 年龄的增加和心脏内干预的数量与AA相关.
- 年龄,心力衰竭史和脂质不良症与血栓栓塞有关.
结论:
- 与普通人群相比,AA在患有CoA的成年人中更常见,但比其他ACHD更少.
- 年龄和心脏内干预是CoA患者AA的显著预测因素.
- 血栓塞栓事件的发生率很低;传统的中风风险因素可能是相关的.
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