夜间脉冲波幅度减弱与长期心血管事件有关
Sobhan Salari Shahrbabaki1, Dominik Linz2, Mathias Baumert1
1School of Electrical and Electronic Engineering, The University of Adelaide, Adelaide, Australia.
International journal of cardiology
|May 31, 2023
概括
通过光聚光学测量 (PPG) 测量的夜间脉冲波幅 (PWA) 变化可以预测心血管事件. 较低的PWA减弱与心血管风险增加有关,特别是在男性和非裔美国人中.
科学领域:
- 心血管研究研究心血管研究
- 生物医学工程 生物医学工程
- 生理学 生理学 生理学
背景情况:
- 摄影电流图 (PPG) 用于脉冲率检测.
- 对心血管 (CV) 事件脉冲波幅 (PWA) 的时间变化的预后价值尚不清楚.
- 调查夜间PWA变异可能会揭示新的心血管风险标志物.
研究的目的:
- 为了量化夜间时间PWA衰减.
- 评估夜间PWA减弱和长期CV事件之间的关联.
- 在一个庞大的多民族人口中评估这种关联.
主要方法:
- 分析了来自1957年多民族动脉样硬化研究参与者的夜间多睡眠记录的PPG数据.
- 夜间PWA衰减指数是计算PWA衰减事件相对于总睡眠时间的累积持续时间.
- 考克斯比例危险分析用于评估与CV事件的关联,平均随访时间为4.9年.
主要成果:
- 夜间PWA减弱指数在男性 (16.3%) 比女性 (14.4%) 高,并且根据种族而异 (华裔美国人:17.9%,非裔美国人:13.5%).
- 夜间PWA减弱指数低于15.2%与心血管事件风险增加有关 (HR=1.58,p=0.042).
- 这种关联在男性和非裔美国人参与者中尤其明显.
结论:
- 夜间PWA衰减指数与心血管事件的风险相反相关.
- 这一PPG衍生指数可以作为一个低成本,可访问的心血管风险标志物.
- 这些发现表明,可以将其集成到消费者可穿戴设备中,以广泛进行心血管风险查.
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