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Updated: Jul 28, 2025

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
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Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

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关键的遗传决定因素驱动食道状细胞癌的启动和免疫逃避

Kyung-Pil Ko1, Yuanjian Huang2, Shengzhe Zhang1

  • 1Department of Experimental Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Gastroenterology
|May 31, 2023
PubMed
概括

丢失TP53,CDKN2A和NOTCH1基因,通过促进细胞变化和免疫逃避,启动食道状细胞癌 (ESCC). 向CCL2可能为这种癌症亚型提供新的治疗策略.

关键词:
在CCL2中,我们可以使用CCL2.这就是CDKN2A.食道状细胞癌 食道状细胞癌免疫逃避是一种免疫逃避.免疫治疗是一种免疫疗法.没有任何东西.器官类动物 器官类动物患者的分层是患者的分层.单细胞RNA的测序这就是TP53的特点.

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