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Updated: Jul 28, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Published on: March 15, 2024

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在脂质过氧化过程中,阿拉基酸的几何异构化会干扰铁化

Yusuke Hirata1, Carla Ferreri2, Yuto Yamada1

  • 1Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6‑3 Aoba, Aramaki, Aoba‑ku, Sendai, Miyagi 980‑8578, Japan.

Free radical biology & medicine
|May 31, 2023
PubMed
概括

多重不和脂肪酸 (mtPUFA) 的单转基因异构体可以防止ferroptosis,一种编程细胞死亡. 与天然的PUFA不同,mtPUFA被纳入细胞膜抑制了铁亡,揭示了对细胞死亡调节的新见解.

关键词:
这是一种Cis-trans异构化.铁化是铁化的一种.自由基是自由基中的一个.脂质过氧化是一种过氧化.在NADPH氧化酶.多重不和脂肪酸 多重不和脂肪酸转化脂肪酸是转化脂肪酸中的一种.

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