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Updated: Jul 28, 2025

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
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A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

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对于11个小分子N-尼托拉胺 (NA) 的可接受摄入量 (AIs)

Joel P Bercu1, Melisa Masuda-Herrera1, Alejandra Trejo-Martin1

  • 1Gilead Sciences, Inc., Nonclinical Safety and Pathobiology (NSP), Foster City, CA, USA.

Regulatory toxicology and pharmacology : RTP
|May 31, 2023
PubMed
概括

卫生当局为制药中的N-尼托拉胺 (NA) 设定了可接受摄入量 (AIs). 这项研究透明地评估了NA毒性数据,以澄清AI衍生,推进对这些潜在致癌物质的风险评估.

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