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下肢骨折开放研究的核心结果

Alexander L Aquilina^1,2, Harry Claireaux¹, Christian O Aquilina³

¹Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Bone & joint research

|May 31, 2023

概括

这项研究建议使用下肢功能量表 (LEFS) 和EuroQol五维五级问卷 (EQ-5D-5L) 来测量成人下肢骨折的核心结果. 这些工具将有助于评估受伤后的流动性和生活质量.

科学领域:

整形外科整形外科整形外科
康复医学康复医学康复医学
临床研究方法论临床研究方法论

背景情况:

成人下肢骨折的核心结局包括步行,步态,移动性,恢复生活角色,疼痛和生活质量.
确定这些核心结果的验证结果测量仪器 (OMI) 对于一致的研究和临床实践至关重要.

研究的目的:

识别和推合适的OMI来测量成人下肢开放骨折中确定的核心结果.
评估现有工具,并列出潜在的候选人来衡量重点复苏方面.

主要方法:

一项系统性审查和质量评估确定了在目标人群中具有良好的测量特性的OMI.
对于尚未在开放下肢骨折中验证的仪器,制定了入围标准.
与患者,医疗保健专业人员和方法学家的共识会议最终确定了OMI建议.

主要成果:

威尔士下肢创伤恢复量表在人口中得到了验证. 十个候选OMI符合入围标准.
对于"行走,步态和流动性"的下肢功能尺度 (LEFS) 和"生活质量"的EuroQol五维五级问卷 (EQ-5D-5L) 达成共识.
对于"重返生活角色"或"疼痛或不适"没有任何仪器达成共识,尽管EQ-5D-5L在实际上提出了一些限制.

结论:

建议使用LEFS和EQ-5D-5L测量成人下肢开放骨折研究和临床实践中的关键结果.
这些仪器为对这一患者群体的流动性和生活质量进行一致评估提供了基础.

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