恶性淋巴瘤与心脏参与的回声心脏学发现:一个单中心的回顾性观察研究
Toshiaki Ebina1, Yuka Sano1, Michiko Hirabayashi1
1Department of Laboratory Medicine and Clinical Investigation, Yokohama City University Medical Center, Japan.
Internal medicine (Tokyo, Japan)
|May 31, 2023
概括
恶性淋巴瘤 (ML) 中心脏参与不常见 (1.5%),特别是在扩散大B细胞淋巴瘤 (DLBCL) 中. 跨胸腔心声学 (TTE) 对于检测心脏问题和监测ML患者治疗反应非常有价值.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 恶性淋巴瘤 (ML) 可以影响任何器官,使心脏参与具有挑战性,在没有明显症状的情况下诊断.
- 在ML中早期发现心脏参与对于患者管理至关重要.
研究的目的:
- 为了确定ML患者心脏参与的发生率.
- 确定与ML中心脏参与相关的跨胸腔心声学 (TTE) 发现.
主要方法:
- 从2013年1月到2019年12月,对453名ML患者进行了回顾性审查.
- 对394名在诊断时或临床过程中接受该程序的患者的TTE数据的分析.
- 评估特定的淋巴瘤亚型,包括扩散性大B细胞淋巴瘤 (DLBCL).
主要成果:
- 在接受了TTE的ML患者中,检测到1.5% (394人中6人) 的心脏参与.
- 扩散性大B细胞淋巴瘤 (DLBCL) 是最常见的与心脏相关的ML类型.
- 五名患者观察到心周溢血;心脏病变不同,大多数患者保持左心室喷射分数.
结论:
- 心脏参与ML是罕见的,但发生,与B细胞淋巴瘤,特别是DLBCL,通常涉及.
- 胸外心声学 (TTE) 是一种有效的非侵入性工具,用于评估ML患者的心脏参与,治疗反应和心脏功能.
- 虽然心周溢出是常见的发现,但ML中心脏病变的谱系是多样化的.
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