在一般日本人口中中风的流行病学:西山研究
Jun Hata1,2, Toshiharu Ninomiya1,2
1Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University.
Journal of atherosclerosis and thrombosis
|May 31, 2023
概括
希萨亚马研究显示,由于更好地控制高血压,中风发生率下降,但新陈代谢风险因素的上升增加了动脉血性和栓塞性中风风险. 新的模型预测了动脉样硬化心血管疾病和心房动风险.
科学领域:
- 流行病学 流行病学
- 心血管疾病研究研究
- 公共卫生 公共卫生
背景情况:
- 成立于1961年的西山研究 (Hisayama Study) 在日本人口中追踪中风,冠状动脉疾病 (CAD) 和非传染性疾病.
- 纵向数据显示,高血压患者的系统血压下降,但代谢风险因素的患病率增加,如肥胖和高胆固醇血症.
- 由于高血压管理的改善,缺血性中风的发生率有所下降,但动脉血性脑梗塞 (ATBI) 和栓塞性中风的比例有所上升.
研究的目的:
- 利用希萨亚马研究数据分析中风发病率和风险因素的长期趋势.
- 审查传统风险因素与中风发展之间的关联.
- 开发动脉样硬化心血管疾病和心房动的风险预测模型.
主要方法:
- 来自西山研究的长度流行病学数据分析.
- 审查现有关于传统风险因素和中风的研究.
- 开发动脉样硬化心血管疾病 (ASCVD) 和心房动 (AF) 的风险预测模型.
主要成果:
- 高血压管理得到了改善,导致缺血性中风率降低.
- 代谢风险因素 (肥胖,高胆固醇血症,葡萄糖不耐受) 的增加.
- 动脉血栓性脑梗塞和栓塞性中风的比例有所上升,这与老龄化人口中的代谢因素和心房有关.
结论:
- 对代谢风险因素和心房的综合管理对于减少ATBI和栓塞性中风风险至关重要.
- 开发的模型旨在在临床实践和健康检查中对ASCVD和AF相关中风的未来风险进行分层.
- 希萨亚马研究为了解和管理一般人群中心血管疾病和中风提供了有价值的长期数据.
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