韩国牛群中Toxoplasma gondii的分子流行病学
1College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea.
Parasites, hosts and diseases
|May 31, 2023
概括
这项研究在韩国牛群中检测到寄生虫Toxoplasma gondii,这是通过未煮熟的肉类对人类的潜在感染来源. 分子分析证实了它的存在,突出了肉类安全的公共卫生问题.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 食物传播的病原体
- 分子流行病学分子流行病学
背景情况:
- 由Toxoplasma gondii引起的 toksoplasmosis 是一个重要的全球公共卫生问题.
- 未熟的肉类消费是人类Toxoplasma gondii感染的主要途径.
- 关于韩国粮食生产牛群中T. gondii的分子流行病学数据有限.
研究的目的:
- 在韩国发现用于人类消费的牛中发现的Toxoplasma gondii菌株的遗传特征.
- 评估韩国牛群中T. gondii的流行率和分子特征.
- 提供韩国牛供应链中T. gondii的基础数据.
主要方法:
- 从韩国金南多的84个农场收集了455只牛的血液样本.
- 利用嵌套PCR进行T. gondii的分子检测.
- 测序B1基因用于检测到的T. gondii分离物的遗传特征.
主要成果:
- 发现T. gondii感染的流行率很低,在455个样本中只有3个 (0.7%) 呈阳性.
- 鉴定T. gondii分离物的B1基因序列与其他已知的T. gondii菌株具有很高的相似性 (97.3-99.6%).
- 这标志着在韩国牛群中首次分子检测T. gondii.
结论:
- 尽管发病率很低,但牛在传染Toxoplasma gondii方面可能构成公共卫生风险.
- 韩国分离物和其他物种的遗传相似性表明潜在的全球菌株特征.
- 强调需要将牛肉中的T. gondii感染视为相关的食品安全问题.
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