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工程 tRNA 抑制细胞和体内无意义突变

Suki Albers1, Elizabeth C Allen2, Nikhil Bharti1

  • 1Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.

Nature
|May 31, 2023
PubMed
概括

研究人员开发了工程转移RNAs (tRNAs) 来抑制无意义突变,这是遗传疾病的常见原因. 这种新疗法恢复了小鼠和人类细胞的功能性蛋白质产生,

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