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血小板输血在早产婴儿:当前的概念和争议-一个系统的审查和元分析
Helena Sofia Ribeiro1, André Assunção2, Rafael José Vieira3,4
1Faculty of Medicine, University of Porto, Porto, Portugal.
European journal of pediatrics
|May 31, 2023
概括
在早产婴儿中,血小板输血 (PTx) 与死亡,败血症和死性肠球炎 (NEC) 的风险增加有关. 需要进一步的研究来澄清这些关联,并优化输血指南.
科学领域:
- 新生儿血液学 新生儿血液学
- 临床儿科 临床儿科
- 基于证据的医学基于证据的医学.
背景情况:
- 新生儿血小板缺血在早产婴儿中很常见,通常用血小板输血 (PTx) 治疗.
- 在这个人群中,PTx的临床益处和危害数据有限.
- 缺乏启动PTx的共识标准.
结论:
- 在早产婴儿的血小板输血与较高的死亡风险,败血症和NEC有关.
- 需要进一步的研究来证实这些关联,特别是IVH,并确定最佳的输血值.
- 有证据表明,PTx可能会造成伤害,需要仔细考虑风险和益处.
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