在计算机断层扫描上周围血管脂肪衰减和心力衰竭与保存的喷射分数的关联
Takahiro Nishihara1, Toru Miyoshi1, Mitsutaka Nakashima1
1Department of Cardiovascular Medicine, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
ESC heart failure
|June 1, 2023
概括
在CT血管学上,冠状周脂肪组织衰减 (PCATA) 是一种新的炎症标志物. 较高的PCATA显着与心力衰竭与保留射出分数 (HFpEF) 相关,这表明炎症是关键机制.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 炎症研究 炎症研究
背景情况:
- 保存喷射分数 (HFpEF) 的心力衰竭与慢性炎症有关.
- 通过冠状动脉计算机断层扫描血管学 (CCTA) 测量的冠状动脉脂肪组织衰减 (PCATA) 是冠状动脉炎症的潜在非侵入性标志物.
研究的目的:
- 调查PCATA与HFpEF存在之间的关联.
- 评估PCATA作为HFpEF中冠状动脉周周炎症的非侵入性标志物.
主要方法:
- 对607名接受CCTA和心声扫描的门诊患者进行了回顾性研究,不包括那些患有阻塞性冠状动脉疾病的患者.
- 评估PCATA是在左前垂下,左环和右冠状动脉的近端40毫米段.
- HFpEF诊断是基于心力衰竭协会 (HFA) -PEFF得分.
主要成果:
- 与对照组相比,HFpEF患者在所有三大冠状动脉 (LAD,LCX,RCA;P<0.01) 中表现出明显更高的PCATA.
- 多变量逻辑回归证实,LAD,LCX和RCA中PCATA较高与HFpEF独立相关 (ORs从1.388到1.634不等).
- PCATA与左心室质量和左心房体积指数有轻微的相关性.
结论:
- 升高的PCATA与HFpEF的存在显著相关.
- 这些发现表明,周冠状脂肪组织内的炎症是导致HFpEF的机制.
相关概念视频
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
46
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
46
Pathophysiology of Heart Failure
1.7K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.7K
Imaging Studies for Cardiovascular System III: X-Ray
219
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
219
Imaging Studies for Cardiovascular System V: CT
45
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
45
Heart Failure II: Pathophysiology
16
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
16
Imaging Studies for Cardiovascular System I:Echocardiography
388
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
388


