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Updated: Jul 28, 2025

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
08:23

CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Published on: November 1, 2024

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针对PCSK9的新方法:小干扰型核糖核酸和基因组编辑

Reindert F Oostveen1, Amit V Khera2, Sekar Kathiresan2

  • 1Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, The Netherlands (R.F.O., E.S.G.S., J.J.P.K.).

Arteriosclerosis, thrombosis, and vascular biology
|June 1, 2023
PubMed
概括

使用RNA干扰和基因组编辑,针对PCSK9 (proprotein convertase subtilisin/kexin type 9) 的新型疗法为患有非常高心血管风险的患者提供了有希望的长效解决方案,这些患者难以达到脂质目标.

关键词:
这是一种Apolipoprotein蛋白.心脏病学心脏病学心脏病学冠状动脉疾病是一种冠状动脉疾病.突变是一种突变.亚提利西尼是亚提利西尼.

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