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Updated: Jul 28, 2025

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生物对等的化物响应性亚酸和基尼尔金点击循环添加在体外和活细胞中

Zhanfeng Hou1, Chuan Wan2, Yun Xing3

  • 1State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.

Organic letters
|June 1, 2023
PubMed
概括

一种新的化物响应点击化学反应为生物对等应用提供了一种简单,无铜的方法. 这种技术使有效的改,蛋白质标记和细胞成像在水性介质中成为可能.

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Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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