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Updated: Jul 28, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

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一个分子蓝图,以准ALK基因融合在质母细胞瘤

Stephen C Mack1,2, Kelsey C Bertrand2,3

  • 1Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.

Clinical cancer research : an official journal of the American Association for Cancer Research
|June 1, 2023
PubMed
概括

无细胞淋巴瘤激酶 (ALK) 基因融合是婴儿质母细胞瘤 (GBM) 的关键驱动因素. 识别这些ALK重组有助于确定那些可以从向ALK疗法中受益的患者.

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Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

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Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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