NIR和THz光谱学:对与尼古丁相关的设备进行实验性调查
Ana-Maria Bratu1, Mihaela Bojan1, Stefan Banita1
1National Institute for Laser, Plasma and Radiation Physics, Bucharest, PO, Romania.
Journal of biophotonics
|June 1, 2023
概括
传统香烟 (TC) 引起的氧化应激比电子香烟更大,这可以通过更高的呼吸乙烯水平来表明. 太赫兹光谱学揭示了TCC.
科学领域:
- 分析化学 分析化学
- 频谱学是一种光谱学.
- 生物标志物 生物标志物
背景情况:
- 氧化压力是吸烟相关健康问题的关键问题.
- 尼古丁输送产品在诱导氧化应激的潜力方面有所不同.
- 呼吸乙烯是氧化应激的一个有效的生物标志物.
研究的目的:
- 为了比较传统香烟 (TC),电子香烟和烟草加热设备引起的氧化应激.
- 使用太赫兹时域光谱学 (THz-TDS) 分析尼古丁输送产品的光谱特性.
- 量化呼吸中的乙烯水平作为氧化应激的生物标志物.
主要方法:
- 利用太赫兹时域光谱学 (THz-TDS) 来分析烟草和尼古丁的传输光谱.
- 采用二氧化碳激光光声谱学 (CO2 LPAS) 系统来测量呼吸中的乙烯度.
- 在TC,电子烟和烟草加热设备的使用者之间比较呼吸中的乙烯水平.
主要成果:
- 与其他产品相比,TC在太赫兹区域表现出更高的传输率.
- 在TC吸烟者 (687ppb) 中,平均呼吸乙烯含量明显高于电子烟 (56ppb) 和烟草加热设备用户 (48ppb).
- 更高的THz传输与增加的氧化应激相关.
结论:
- 与电子烟和烟草加热设备相比,传统香烟会引起更高水平的氧化应激.
- THz-TDS可以提供有关氧化应激的吸烟产品的物理特性.
- 呼吸乙烯是吸烟引起的氧化应激的可靠指标.
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