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Updated: Jun 21, 2026

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
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一个基因组分数来预测用辐射管理的大脑转移患者的局部控制

Nayan Lamba1,2, Daniel N Cagney3, Paul J Catalano4

  • 1Harvard Radiation Oncology Program, Harvard University, Boston, Massachusetts, USA.

Neuro-oncology
|June 1, 2023
PubMed
概括

开发了一种新的基于DNA的"脑辐射预测分数" (Brain-RPS),用于预测放射治疗后脑转移患者的局部复发风险. 这种基因组分数可能有助于个性化对大脑转移的辐射治疗.

关键词:
大脑转移是大脑转移.基因组学就是基因组学.当地复发局部复发辐射治疗疗法 辐射治疗疗法

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...