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Updated: Jul 28, 2025

Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
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Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

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精制基因组决定因素,以逃避X染色体失活的基础

Samantha Peeters1, Tiffany Leung1,2, Oriol Fornes1,2

  • 1Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

NAR genomics and bioinformatics
|June 1, 2023
PubMed
概括

雌性哺乳动物通过X染色体失活 (XCI) 沉默一个X染色体. 研究人员确定了足够的基因促销元件来驱动从XCI逃脱,这对于理解基因表达差异和X无倍化症至关重要.

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