霍乱感染风险和霍乱疫苗在怀孕期间的安全性
Pamela El Hayek1,2, Myriam Boueri1, Leah Nasr1
1Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Lebanese American University School of Medicine, Lebanon.
Infectious diseases in obstetrics and gynecology
|June 1, 2023
概括
霍乱感染对孕妇,胎儿和新生儿构成重大风险,增加死产和新生儿死亡. 霍乱疫苗在怀孕期间是安全的,并减少胎儿和新生儿并发症.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 霍乱感染在怀孕期间带来了独特的挑战,影响了母亲和胎儿的结果.
- 了解孕妇霍乱相关的风险对于有效的管理和预防至关重要.
研究的目的:
- 审查霍乱感染对孕妇,胎儿和新生儿的影响.
- 评估霍乱疫苗在孕妇中的安全性和有效性.
主要方法:
- 2022年11月对科学文献进行了叙述性审查.
- 搜索的数据库包括PubMed,Scopus,SciELO,CINAHL,科学网和科学直播.
- 从24项研究中提取和分析了数据.
主要成果:
- 霍乱感染显著增加死胎和新生儿死亡的风险,特别是在第三个三个月,观察到自发流产.
- 新生儿死亡率与先天性形和低Apgar分数有关.
- 与未接种疫苗的对照组相比,霍乱疫苗在怀孕期间显示出安全性,并减少了接种疫苗的妇女的胎儿和新生儿形.
结论:
- 霍乱感染对怀孕构成严重威胁,导致胎儿和新生儿的不良后果.
- 霍乱疫苗接种是一种安全有效的策略,可以减轻孕妇的这些风险.
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