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Updated: Jul 28, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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衰老会影响哺乳动物中央时钟中的GABAergic功能和平衡

Anneke H O Olde Engberink1, Pablo de Torres Gutiérrez1, Anna Chiosso1

  • 1Laboratory for Neurophysiology, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.

Frontiers in neuroscience
|June 1, 2023
PubMed
概括

衰老会破坏大脑的中心昼夜时钟,即上核 (SCN),通过改变激发/抑制 (E/I) 平衡. 这导致神经元同步减少,老哺乳动物的生物节奏较弱.

关键词:
的成像成像技术可以帮助我们.化物运输器 化物运输器昼夜活动时间 (Circadian)激发性/抑制性的平衡.这是一只老老鼠.上的核是一个上的核.

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